The overwhelming majority of MPI studies are now performed using SPECT and electrocardiographic (ECG) gating, which further add to the complexity of the study. Whereas MPI is a valuable diagnostic tool, it is also a complex physiologic imaging process, which exposes it to several potential pitfalls and artifacts that can limit the utility of the study. The clinical importance of MPI is in part reflected in its use, with annual double-digit growth ( 1). With its unique ability to evaluate perfusion at the cellular level and to assess perfusion at peak exercise stress, MPI plays an important role in diagnosing cardiovascular disease, establishing prognosis, assessing the effectiveness of therapy, and evaluating viability. Myocardial perfusion imaging (MPI) is a valuable tool in the management of patients with cardiovascular disease.
It also presents an enormous societal burden with respect to morbidity, health care expense, and personal hardship.
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The reader should develop an understanding of steps to limit these factors, actions to correct them if they do arise and, when necessary, how to incorporate their influence into the interpretation of the study.Ĭardiovascular disease is the number one cause of death in North America. After reviewing this article, the reader should be familiar with the causes and the effects of these potential artifacts and pitfalls. These factors may be related to the patient (including unique aspects of the patient's heart), the nuclear medicine equipment, or the actions of the technologist. However, MPI is a complex process, subject to a variety of artifacts and pitfalls, which may limit its clinical utility. MPI plays a key role in diagnosing cardiovascular disease, establishing prognosis, assessing the effectiveness of therapy, and evaluating viability. Myocardial perfusion imaging (MPI) is an important imaging modality in the management of patients with cardiovascular disease.
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